Evolution of the Unknown is a symposium which invites participants whose work is on the horizon of the known, from various fields, across science, astronomy, astrophysics, astrobiology, arts, humanities, history, and other less traditional fields of study. We come together to share our experiences of confronting the unknown, and the impact of the unknown on culture and imagination. Participants are also encouraged to bring any experiments or works they have made that may create encounters with the unknown, in a form that others may interact with. It will also be an opportunity for an experiment in the unknown that will be run during the symposium, with participation from attendees.